Abdominal or stomach cramping or burning (severe); abdominal or stomach pain; backache; bloody, black, or tarry stools; cough or hoarseness. Stomach upset from popping prednisone is a common complaint, says Boomershine. The easy fix: take it with food to prevent nausea from. Prednisone should never be taken on an empty stomach. It is usually best to take it in the morning, after breakfast and before 9 a.m. If your child needs to take. Osteoporosis weakening of bones. Need Help Finding a Physician? Fookes, BPharm Last updated on Apr 3, Reading about these prednisone causing cushings disease effects may make you uncomfortable about taking steroids. While we encourage individuals to share their personal experiences with Continue reading, please consult a physician before making changes to your own COPD management plan. Others, such as getting a rounder face, happen after weeks or months. The human body makes a hormone that is very similar to prednisone. Sign In to Participate Or register to become a member. Never stop prednisone suddenly if you have been taking it for a long period of time. Updated Feb Prednisone may be used in low doses for long-term immunosuppression or in higher doses for treatment of rejection. The coordinator can help arrange for your child to receive prednisone intravenously. Missed Doses If your child misses a dose of prednisone, call your coordinator for advice. Because prednisone inhibits the immune system, it decreases the ability to fight infection.